Intestinal polyposis associated with melanosis oris.

Weber (1919) described a case of acute intussusception in one of a pair of twins originally noticed by Hutchinson (1896) to have oral pigmentation. Peutz (1921) recorded a family of seven, and Jeghers, McKusick and Katz (1949) reported 10 cases of melanosis of the lips and buccal mucosa together with polyposis of the gastro-intestinal tract. The latter's report included a review of the literature. Since then 45 cases have been recorded in the world literature, 15 of these in England (Foster, 1944; Tanner, 1951; Wolff, 1952; Kitchin, 1953; Hunter and Wilson, 1953; Smith, 1954; Savage, 1954; Young, 1954; Walker-Brash, 1954; Crone and Light, 1954). The case recorded here is probably an example of this syndrome although not yet proven.